Idiosyncratic Drug Actions

Idiosyncratic drug reactions are unpredictable and unique adverse drug reactions that occur in a small percentage of individuals. These reactions are not necessarily related to the dose or frequency of the drug, but rather to the individual’s genetic or environmental makeup.

Idiosyncratic drug reactions (IDRs) are a significant cause of morbidity and mortality for patients; they also markedly increase the uncertainty of drug development. The major targets are skin, liver, and bone marrow. Examples of idiosyncratic drug reactions include anaphylaxis, Stevens-Johnson syndrome, and toxic epidermal necrolysis.

Homeopathy harnesses the property of IDRs in a very novel way.